Search 1,000 of PHOTOS Katherine Marie Heigl (born November 24, 1978) is an American actress. She was best known for her role as Dr. Izzie Stevens on ABC's Grey's Anatomy from 2005 to 2010. She has also starred in films such as Knocked Up, Zyzzyx Road, 27 Dresses, The Ugly Truth, Killers, and Life As We Know It.
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27 Dresses 2008 dir. Anne Fletcher Cast Brian Kerwin Charli Barcena
The Ugly Truth 2009 dir. Robert Luketic Starring Katherine Heigl Butler
Killers dir. Robert Luketic Stars Katherine Heigl Ashton Kutcher